Tetrahydrofuran is a heterocyclic organic compound with the molecular formula C4H8O. Belonging to the ether class, it is a fully hydrogenated product of the aromatic compound furan. It is a colorless, water miscible organic liquid with low viscosity at room temperature and pressure. The chemical formula of this cyclic ether can be written as (CH2) 4O. Due to its long liquid range, it is a commonly used medium polarity non protonic solvent. Its main use is as a precursor for high molecular weight polymers. Although THF has a similar odor and chemical properties to ether, its anesthetic effect is poor.

Health hazard

After inhaling high concentrations, symptoms such as dizziness, headache, chest tightness, chest pain, cough, fatigue, stomach pain, dry mouth, nausea, vomiting, and eye irritation may occur. Some patients may experience liver dysfunction. The concentration of THF in urine is related to the concentration of THF in the environment, and it can also cause nosebleeds, gastric bleeding, and ulcers; High doses or repeated exposure may lead to hepatic fat infiltration and cell lysis. Directly applying a 20% aqueous solution to human skin can cause moderate skin irritation, while a 50% aqueous solution can cause severe corrosive damage. 20% aqueous solution can cause serious corneal damage to the human eye: long-term exposure can lead to loss of sexual function, fertility, or kidney disease!

Hazardous characteristics

Its vapor can form explosive mixtures with air. Exposure to high heat, open flames, and strong oxidants can easily cause combustion. Exposure to air or exposure to light can generate peroxides with potential explosive hazards. Reactions can occur when in contact with acids. Its vapor is heavier than air and can spread to a considerable distance at lower levels. It will ignite and reignite when exposed to a source of fire.