Part One: Chemicals

Chemical Chinese name: Trichloromethane

Chemical English name: trichloromethane

Chinese name 2: Chloroform

English name 2: Chloroform

Part 2: Overview of Hazards

Hazard Category: Class 6.1 Toxic Substances

Invasion routes: inhalation, ingestion, transdermal absorption

Health hazards: mainly affecting the central nervous system, having anesthetic effects, and causing damage to the heart, liver, and kidneys. Acute poisoning: Inhalation or absorption through the skin can cause acute poisoning. In the initial stage, there are symptoms such as headache, dizziness, nausea, vomiting, excitement, damp and hot skin, and mucosal irritation. In the future, there will be mental disorders, shallow breathing, disappearance of reflexes, coma, and in severe cases, respiratory paralysis and ventricular fibrillation. It may also be accompanied by liver and kidney damage. When accidentally poisoned, there is a burning sensation in the stomach accompanied by nausea, vomiting, abdominal pain, and diarrhea. Symptoms of anesthesia will appear in the future. Liquid can cause dermatitis, eczema, and even skin burns. Chronic effects: Mainly causing liver damage, with symptoms such as indigestion, fatigue, headache, insomnia, and a few cases of kidney damage and chloroform addiction.

Environmental hazards: Harmful to the environment and can cause pollution to water bodies.

Explosive hazard: This product is non flammable, toxic, suspected carcinogen, and irritating.

Part Three: Composition/Composition Information

Main ingredients: Trichloromethane content: 99.0% pure product

CAS number: 67-66-3

Relative molecular weight: 119.39

Molecular formula: CHCl3

Part Four: First Aid Measures

Skin contact: Immediately remove contaminated clothing and rinse with plenty of flowing water for at least 15 minutes. Seek medical attention.

Eye contact: Immediately lift the eyelids and thoroughly rinse with plenty of flowing water or saline solution for at least 15 minutes. Seek medical attention.

Inhalation: Quickly leave the scene and move to a place with fresh air. Keep the respiratory tract unobstructed. If breathing is difficult, administer oxygen. If breathing stops, immediately perform artificial respiration. Seek medical attention.

Ingestion: Drink plenty of warm water and induce vomiting. Seek medical attention.

Part 5: Fire Protection Measures

Hazardous characteristics: When in contact with open flames or hot objects, it can produce highly toxic phosgene. Under the action of air, moisture, and light, acidity increases, making it highly corrosive to metals.

Harmful combustion products: hydrogen chloride, phosgene.

Fire extinguishing method: Firefighters must wear filter type gas masks (full face shields) or isolated respirators, wear full body fire and gas protective clothing, and extinguish the fire in the upwind direction. Fire extinguishing agents: misty water, carbon dioxide, sand.

Part 6: Emergency Response to Leakage

Emergency response: Quickly evacuate personnel from the contaminated area to a safe zone, isolate them, and strictly restrict their entry and exit. It is recommended that emergency responders wear self-contained positive pressure respirators and protective clothing. Do not come into direct contact with the leaked material. Cut off the leakage source as much as possible.

Minor leakage: Absorb with sand, vermiculite, or other inert materials.

Massive leakage: Construct embankments or dig pits to contain it. Cover with foam to reduce steam disaster. Transfer to a tanker or dedicated collector using a pump, and recycle or transport to a waste disposal site for disposal.

Part 7: Handling and Storage

Precautions for operation: Closed operation, local exhaust. Operators must undergo specialized training and strictly adhere to operating procedures. It is recommended that operators wear direct gas masks (half face masks), chemical safety goggles, work clothes that prevent toxic substances from penetrating, and chemical resistant gloves. Prevent steam leakage into the workplace air. Avoid contact with alkalis and aluminum. Handle with care during transportation to prevent damage to packaging and containers. Equip with emergency response equipment for leaks. Empty containers may contain residual harmful substances.

Storage precautions: Store in a cool and ventilated warehouse. Stay away from sources of fire and heat. The storage temperature shall not exceed 30 ℃, and the relative humidity shall not exceed 80%. Keep the container sealed. It should be stored separately from alkaline, aluminum, and edible chemicals, and avoid mixing storage. The storage area should be equipped with emergency response equipment for leaks and suitable containment materials.

Part 8: Contact Control/Personal Protection

China MAC (mg/m3): 20

Monitoring method: Gas chromatography

Engineering control: Closed operation, local exhaust.

Respiratory protection: When the concentration in the air exceeds the standard, a direct gas mask (half face mask) should be worn. Wear an air respirator during emergency rescue or evacuation.

Eye protection: Wear chemical safety goggles.

Body protection: Wear work clothes that prevent toxic substances from penetrating.

Hand protection: Wear chemical resistant gloves.

Other protections: Smoking, eating, and drinking are prohibited at the work site. After work, take a shower and change clothes. Store clothes contaminated with toxic substances separately and wash them for later use. Pay attention to personal hygiene and cleanliness.

Part 9: Physical and Chemical Characteristics

Appearance and characteristics: Colorless and transparent heavy liquid, highly volatile, with a special odor.

Melting point (℃): -63.5

Boiling point (℃): 61.3

Relative density (water=1): 1.50

Relative vapor density (air=1): 4.12

Saturated vapor pressure (kPa): 13.33 (10.4 ℃)

Combustion heat (kJ/mol): No data available

Critical temperature (℃): 263.4

Critical pressure (MPa): 5.47

Logarithmic value of octanol/water partition coefficient: 1.97

Flash point (℃): No data available

Ignition temperature (℃): No data available

Explosion upper limit% (V/V): No data available

Lower explosive limit% (V/V): No data available

Solubility: Insoluble in water, soluble in alcohols, ethers, and benzene.

Main applications: Used for organic synthesis and anesthesia.

Part 10: Stability and Reactivity

Stability: Stable

Prohibited substances: alkalis, aluminum.

Condition to avoid contact: light exposure.

Aggregation hazard: non aggregation

Decomposition products: hydrogen chloride, phosgene

Part 11: Toxicological Data

Acute toxicity: LD50: 908 mg/kg (oral administration in rats) LC50: 47702mg/m3, 4 hours (inhalation in rats)

Subacute and chronic toxicity: Chronic toxicity in animals mainly manifests as liver and kidney damage

Stimulus: No data available

Allergenicity: No data available

Mutability: No data available

Teratoxicity: No data available

Carcinogenicity: IARC Carcinogenicity Review: May be carcinogenic to humans

Part 12: Ecological Data

Ecotoxicity: No data available

Biodegradability: No data available

Non biodegradable: No data available

Bioaccumulation or Bioaccumulation: No data available

Other harmful effects: This substance is harmful to the environment and can accumulate in groundwater. Its pollution behavior is mainly reflected in drinking water, but it can also cause pollution to food and vegetables. Disrupting the respiratory system of sensitive aquatic organisms. It is difficult to biodegrade in aquatic environments.

Part 13: Disposal of Waste

Waste nature: hazardous substance

Disposal method: Use incineration method for disposal. Mix with fuel and then incinerate. The hydrogen halide discharged from the incinerator is removed by an acid scrubber.

Disposal precautions: Before disposal, relevant national and local regulations should be consulted.

Part 14: Transportation Information

Dangerous Goods Number: 61553

UN number: 1888

Packaging label: Toxic substances

Packaging category: Class III packaging

Packaging method: Small opening steel drum; Ordinary wooden box outside the ampoule bottle; Screw mouth glass bottles, iron cap pressed mouth glass bottles, plastic bottles, or ordinary wooden boxes outside metal drums (cans); Threaded glass bottles, plastic bottles, or tin plated steel drums (cans) are filled with bottom plate flower boxes, fiberboard boxes, or plywood boxes.

Transportation precautions: During railway transportation, the dangerous goods loading table in the "Dangerous Goods Transport Rules" of the Ministry of Railways should be strictly followed for loading. Before transportation, the packaging container should be checked for completeness and sealing. During transportation, it is necessary to ensure that the container does not leak, collapse, fall, or damage. It is strictly prohibited to mix with acids, oxidants, food, and food additives during transportation. Transport vehicles should be equipped with leak emergency response equipment during transportation. During transportation, it should be protected from direct sunlight, rain, and high temperatures. When transporting by road, follow the prescribed route and do not stay in residential or densely populated areas.

Part 15: Regulatory Information

Regulatory information: Regulations on the Safety Management of Hazardous Chemicals (State Council Decree No. 591, implemented on December 1, 2011), Regulations on the Safe Use of Chemicals in the Workplace (issued by the Ministry of Labor and the Ministry of Chemical Industry on December 20, 1996), and other regulations have made corresponding provisions for the safe use, production, storage, transportation, loading and unloading of hazardous chemicals; The classification and hazard disclosure of commonly used hazardous chemicals (GB 13690-2009) classifies the substance as a Class 6.1 toxic substance; Trichloromethane in the workshop air

The national standard (GB 16219-1996) specifies the maximum allowable concentration and detection method of this substance in workshop air.

Part 16: Other Information

References:

1. Zhou Guotai, Complete Book of Chemical Hazardous Materials Safety Technology, Chemical Industry Press, 1997

2. Compiled by the Toxic Chemicals Management Office of the National Environmental Protection Administration and the Beijing Institute of Chemical Technology, Environmental Data Manual for Chemical Toxicity Regulations, China Environmental Science Press, 1992