Part One: Chemicals

Chemical Chinese: Butanone

Chemical English name: 2-butanone

Chinese name 2: Methyl ethyl ketone

Main uses: Used as a solvent, dewaxing agent, as well as in various organic synthesis, and as a raw material for the synthesis of fragrances and pharmaceuticals.

Restricted use: Prohibited from being used for the production of narcotics

Part 2: Overview of Hazards

Hazard category: Flammable liquid with flash point in Class 3.2

Invasion routes: inhalation, ingestion, transdermal absorption.

Health hazards: Irritating to the eyes, nose, throat, and mucous membranes. Long term exposure can cause dermatitis. This product is often used in combination with hexanone [2] to enhance the peripheral neuropathy caused by hexanone [2], but no peripheral neuropathy was found when exposed to butanone alone.

Environmental hazards: This substance may pose a threat to the environment and should be given special attention to water bodies

Explosive hazard: This product is flammable and irritating.

Part Three: Composition/Composition Information

Main ingredients: Butanone content: 99.0% pure product

CAS number: 78-93-3

Relative molecular weight: 72.11

Molecular formula: C4H8O

Part Four: First Aid Measures

Skin contact: Remove contaminated clothing and thoroughly rinse the skin with soap and water.

Eye contact: Lift the eyelids and rinse with flowing water or saline solution. Seek medical attention.

Inhalation: Quickly leave the scene and move to a place with fresh air. Keep the respiratory tract unobstructed. If breathing is difficult, administer oxygen. If breathing stops, immediately perform artificial respiration. Seek medical attention.

Ingestion: Drink plenty of warm water and induce vomiting. Seek medical attention.

Part 5: Fire Protection Measures

Hazardous characteristics: Flammable, its vapor can form explosive mixtures with air, and there is a risk of combustion and explosion when exposed to open flames, high heat, or oxidants. Its vapor is heavier than air and can spread to a considerable distance at lower levels. It will ignite and reignite when exposed to a source of fire.

Harmful combustion products: carbon monoxide, carbon dioxide.

Fire extinguishing method: Move the container from the fire scene to an open area as much as possible. Spray water to keep the fire container cool until the fire is extinguished. If the container in the fire has changed color or produced sound from the safety relief device, it must be evacuated immediately.

Extinguishing agent: insoluble foam, dry powder, carbon dioxide, sand.

Part 6: Emergency Response to Leakage

Emergency response: Quickly evacuate personnel from the contaminated area to a safe zone, isolate them, and strictly restrict their entry and exit. Cut off the fire source. It is recommended that emergency personnel wear self-contained positive pressure respirators and anti-static work clothes. Cut off the leakage source as much as possible. Prevent the flow into restricted spaces such as sewers and drainage ditches.

Minor leakage: Absorb or absorb with sand or other non combustible materials. You can also rinse with a large amount of water, dilute the washing water, and put it into the wastewater system.

Massive leakage: Construct embankments or dig pits to contain it. Cover with foam to reduce steam disaster. Transfer to a tanker or dedicated collector using an explosion-proof pump, and recycle or transport to a waste disposal site for disposal.

Part 7: Handling and Storage

Precautions for operation: Closed operation, comprehensive ventilation. Operators must undergo specialized training and strictly adhere to operating procedures. It is recommended that operators wear self-priming filter type gas masks (half masks), chemical safety goggles, anti-static work clothes, and rubber oil resistant gloves. Keep away from sources of fire and heat, and smoking is strictly prohibited in the workplace. Use explosion-proof ventilation systems and equipment. Prevent steam leakage into the workplace air. Avoid contact with oxidants, reducing agents, and alkalis. During filling, the flow rate should be controlled and there should be a grounding device to prevent static electricity accumulation. Handle with care during transportation to prevent damage to packaging and containers. Equip with corresponding types and quantities of fire-fighting equipment and emergency response equipment for leaks. Empty containers may contain residual harmful substances.

Storage precautions: Store in a cool and ventilated warehouse. Stay away from sources of fire and heat. The storage temperature should not exceed 30 ℃. Keep the container sealed. It should be stored separately from oxidants, reducing agents, and alkalis, and avoid mixing storage. Adopt explosion-proof lighting and ventilation facilities. Prohibit the use of mechanical equipment and tools that are prone to generating sparks. The storage area should be equipped with emergency response equipment for leaks and suitable containment materials.

Part 8: Contact Control/Personal Protection

Occupational exposure limit

China MAC (mg/m3): No standard established

Monitoring method: Gas chromatography

Engineering control: The production process is sealed and fully ventilated.

Respiratory protection: When the concentration in the air exceeds the standard, wear a self-priming filter type gas mask (half face mask).

Eye protection: If necessary, wear chemical safety goggles.

Body protection: Wear anti-static work clothes.

Hand protection: Wear rubber oil resistant gloves.

Other protections: Smoking is strictly prohibited at the work site. Pay attention to personal hygiene and cleanliness. Avoid long-term repeated exposure.  

Part 9: Physical and Chemical Characteristics

Appearance and characteristics: Colorless liquid with a smell similar to acetone.

Melting point (℃): -85.9

Boiling point (℃): 79.6

Relative density (water=1): 0.81

Relative vapor density (air=1): 2.42

Saturated vapor pressure (kPa): 9.49 (20 ℃)

Heat of combustion (kJ/mol): 2441.8

Critical temperature (℃): 260

Critical pressure (MPa): 4.40

Logarithmic value of octanol/water partition coefficient: 0.29

Flash point (℃): -9

Ignition temperature (℃): 404

Explosion upper limit% (V/V): 11.4

Lower explosive limit% (V/V): 1.7

Solubility: soluble in water, ethanol, ether, and miscible with oils

Main uses: Used as a solvent, dewaxing agent, as well as in various organic synthesis, and as a raw material for the synthesis of fragrances and pharmaceuticals.

Part 10: Stability and Reactivity

Stability: Stable

Prohibited substances: strong oxidants, alkalis, strong reducing agents.

Conditions to avoid contact: open flames, high heat

Aggregation hazard: non aggregation

(Combustion) decomposition products: carbon monoxide, carbon dioxide

Part 11: Toxicological Data

Acute toxicity: LD50: 3400 mg/kg (oral administration in rats); 6480 mg/kg (rabbit transdermal) LC50: 23520mg/m3, 8 hours (rat inhalation)

Irritation: Rabbit via eye: 80mg, causing irritation. Rabbit percutaneous open stimulation test: 13780 μ g/24 hours, mild stimulation.

Mutability: Sex chromosome loss and non segregation: Saccharomyces cerevisiae 33800ppm.

Reproductive motherhood: Inhalation of the lowest toxic pesticide concentration (TCL0) in rats: 3000ppm (7 hours), (6-15 days of pregnancy), causing abnormal development of the craniofacial region (including nose and tongue), abnormal development of the urea secretion reproductive system, and abnormal coagulation.

Part 12: Ecological Data

Ecotoxicity: No data available.

Biodegradability: No data available.

Non biodegradable: No data available.

Bioaccumulation or Bioaccumulation: No data available.

Other harmful effects: No information available.

Part 13: Disposal of Waste

Waste nature: hazardous waste

Disposal method: Use incineration method for disposal.

Disposal precautions: Before disposal, relevant national and local regulations should be consulted.

Part 14: Transportation Information

Dangerous Goods Number: 32073

UN number: 1193

Packaging label: Flammable liquid

Packaging category: Class II packaging

Packaging method: Small opening steel drum; Ordinary wooden box outside the ampoule bottle; Screw mouth glass bottles, iron cap pressed mouth glass bottles, plastic bottles, or ordinary wooden boxes outside metal drums (cans).

Transportation precautions: During transportation, the transport vehicle should be equipped with corresponding types and quantities of fire-fighting equipment and emergency response equipment for leaks. It is best to transport in the morning and evening during summer. The tank truck used for transportation should have a grounding chain, and a perforated partition can be installed inside the tank to reduce static electricity generated by vibration. It is strictly prohibited to mix and transport with oxidants, reducing agents, alkalis, edible chemicals, etc. During transportation, it should be protected from direct sunlight, rain, and high temperatures. When stopping midway, one should stay away from sources of fire, heat, and high temperature areas. The exhaust pipe of the vehicle carrying the item must be equipped with a flame retardant device, and the use of mechanical equipment and tools that are prone to generating sparks for loading and unloading is prohibited. When transporting by road, follow the prescribed route and do not stay in residential or densely populated areas. It is prohibited to slip during railway transportation. It is strictly prohibited to use wooden boats or cement boats for bulk transportation.

Part 15: Regulatory Information

Regulatory information: Regulations on the Safety Management of Hazardous Chemicals (State Council Decree No. 591, implemented on December 1, 2011), Regulations on the Safe Use of Chemicals in the Workplace (issued by the Ministry of Labor and the Ministry of Chemical Industry on December 20, 1996), and other regulations have made corresponding provisions for the safe use, production, storage, transportation, loading and unloading of hazardous chemicals; The classification and hazard disclosure of commonly used hazardous chemicals (GB 13690-2009) classifies the substance as a Class 3.2 flammable liquid with a flash point.

Part 16: Other Information

References:

1. Zhou Guotai, Complete Book of Chemical Hazardous Materials Safety Technology, Chemical Industry Press, 1997

2. Compiled by the Toxic Chemicals Management Office of the National Environmental Protection Administration and the Beijing Institute of Chemical Technology, Environmental Data Manual for Chemical Toxicity Regulations, China Environmental Science Press, 1992