Acetonitrile MSDS_Surpose Density_CAS Number

2021-01-27
Part 1: Chemical Name
Chemical Chinese name:
acetonitrile
Chemical English name:
acetonitrile
Chinese name 2:
Methyl cyanide
English name 2:
methyl cyanide
Technical manual code:
414
CAS No. ：
75-05-8
Molecular formula:
C2H3N
Molecular weight:
41.05
Part 2: Composition/Composition Information
hazardous substance components
content
CAS No.
acetonitrile

75-05-8
Part Three: Overview of Hazards
Hazard category:

Invasion route:
Inhalation, ingestion, and absorption through the skin.
Health hazards:
Acute acetonitrile poisoning occurs slower than hydrocyanic acid, with a latent period of several hours. The main symptoms are weakness, powerlessness, pale complexion, nausea, vomiting, abdominal pain, diarrhea, chest tightness, and chest pain; Severe cases may have respiratory and circulatory system disorders, shallow, slow and irregular breathing, decreased blood pressure, fine and slow pulse, decreased body temperature, paroxysmal convulsions, and coma. There may be urinary frequency, proteinuria, etc.
Environmental hazards:
May cause pollution to water bodies, soil, and atmosphere.
Explosive hazard:
This product is flammable.
Part Four: First Aid Measures
Skin contact:
Remove contaminated clothing and thoroughly rinse the skin with soap and water.
Eye contact:
Lift the eyelids and rinse with flowing water or saline solution. Seek medical attention.
Inhalation:
Quickly evacuate the scene to a place with fresh air. Keep the respiratory tract unobstructed. If breathing is difficult, administer oxygen. If breathing stops, immediately perform artificial respiration. Seek medical attention.
Ingestion:
Drink plenty of warm water and induce vomiting. Wash the stomach with a 1:5000 potassium permanganate or 5% sodium thiosulfate solution. Seek medical attention.
Part 5: Fire Protection Measures
Hazardous characteristics
Flammable, its vapor can form explosive mixtures with air, and there is a risk of combustion and explosion when exposed to open flames, high heat, or contact with oxidants. Can react strongly with oxidants. There is a glowing flame when burning. Reacts violently with sulfuric acid, fuming sulfuric acid, chlorosulfonic acid, perchlorate, and other substances.
Harmful combustion products:
Carbon monoxide, carbon dioxide, nitrogen oxides, hydrogen cyanide.
Fire extinguishing methods:
Spray water to cool the container, and if possible, move the container from the fire scene to an open area. Extinguishing agent: insoluble foam, dry powder, carbon dioxide, sand. Using water to extinguish the fire is ineffective.
Part 6: Emergency Response to Leakage
Emergency response:
Quickly evacuate personnel from the contaminated area to a safe zone, isolate them, and strictly restrict their entry and exit. Cut off the fire source. It is recommended that emergency responders wear self-contained positive pressure respirators and protective clothing. Do not come into direct contact with the leaked material. Cut off the leakage source as much as possible. Prevent the flow into restricted spaces such as sewers and drainage ditches. Minor leakage: Absorb with activated carbon or other inert materials. You can also rinse with a large amount of water, dilute the washing water, and put it into the wastewater system. Massive leakage: Construct embankments or dig pits to contain it. Spray like water cools and dilutes steam, protects on-site personnel, and dilutes leakage into incombustible materials. Transfer to a tanker or dedicated collector using an explosion-proof pump, and recycle or transport to a waste disposal site for disposal.
Part 7: Handling and Storage
Precautions for operation:
Strictly seal and provide sufficient local exhaust and comprehensive ventilation. Operate as mechanically and automatically as possible. Operators must undergo specialized training and strictly adhere to operating procedures. It is recommended that operators wear filter type gas masks (full face shields), self-contained breathing apparatus or ventilated respirators, rubber protective clothing, and rubber oil resistant gloves. Keep away from sources of fire and heat, and smoking is strictly prohibited in the workplace. Use explosion-proof ventilation systems and equipment. Keep away from flammable and combustible materials. Prevent steam leakage into the workplace air. Avoid contact with oxidants, reducing agents, acids, and bases. Handle with care during transportation to prevent damage to packaging and containers. Equip with corresponding types and quantities of fire-fighting equipment and emergency response equipment for leaks. Empty containers may contain residual harmful substances.
Storage precautions:
Store in a cool and ventilated warehouse. Stay away from sources of fire and heat. The storage temperature should not exceed 30 ℃. Keep the container sealed. It should be stored separately from oxidants, reducing agents, acids, bases, flammable materials, and edible chemicals, and should not be stored together. Adopt explosion-proof lighting and ventilation facilities. Prohibit the use of mechanical equipment and tools that are prone to generating sparks. The storage area should be equipped with emergency response equipment for leaks and suitable containment materials.
Part 8: Contact Control/Personal Protection
Occupational exposure limit

China MAC(mg/m3) ：
3
The former Soviet Union MAC(mg/m3) ：
10
TLVTN ：
OSHA 40ppm,67mg/m3; ACGIH 40ppm,67mg/m3
TLVWN ：
ACGIH 60ppm,101mg/m3
Monitoring method:
gas chromatography
Engineering control:
Strictly seal and provide sufficient local exhaust and comprehensive ventilation. Mechanize and automate as much as possible. Provide safety shower and eye wash equipment.
Respiratory protection:
When exposed to toxic substances, it is necessary to wear a filtered gas mask (full face mask), self-contained breathing apparatus, or ventilated respirator. Wear an air respirator during emergency rescue or evacuation.
Eye protection:
Respiratory protection has been implemented.
Body protection:
Wear adhesive protective clothing.
Hand protection:
Wear rubber oil resistant gloves.
Other protections:
Smoking, eating, and drinking are prohibited on the work site. Work completed, thoroughly cleaned. Store clothes contaminated with toxic substances separately and wash them for later use. The workshop should be equipped with first aid equipment and medication. Homeworkers should learn to self rescue and mutual aid.
Part 9: Physical and Chemical Characteristics
Main ingredients:
of the purest quality
Appearance and characteristics:
Colorless liquid with a pungent odor.
pH ：

Melting point ( ℃ ) ：
-45.7
Boiling point ( ℃ ) ：
81.1
Relative density (water=1):
0.79
Relative vapor density (air=1):
1.42
Saturated vapor pressure (kPa):
13.33(27℃)
Combustion heat (kJ/mol):
1264.0
Critical temperature (℃):
274.7
Critical pressure (MPa):
4.83
Logarithmic value of octanol/water partition coefficient:
-0.34
Flash point (℃):
2
Ignition temperature (℃):
524
Explosion upper limit% (V/V):
3.0
Lower explosive limit% (V/V):
16.0
Solubility:
It is miscible with water and soluble in most organic solvents such as alcohols.
Main purpose:
Used for the production of drugs such as vitamin B1, as well as fragrances, fatty acid extraction, etc.
Other physical and chemical properties:

Part 10: Stability and Reactivity
Stability:

Prohibited substances:
Acid, alkali, strong oxidizing agent, strong reducing agent, alkali metal.
Conditions to avoid contact:

Aggregation hazards:

Decomposition products:

Part 11: Toxicological Data
Acute toxicity:

LD50: 2730 mg/kg (oral administration in rats); 1250 mg/kg (rabbit transdermal)

LC50 ： 12663mg/m3 ， 8 hours (inhaled by rats)

Subacute and chronic toxicity:

Thrill:
Mg/kg/20 days, 20mg, severe irritation. Rabbit percutaneous open stimulation test: 500mg, mild stimulation.
Allergenicity:

Mutability:

Teratoxicity:

Carcinogenicity:

Part 12: Ecological Data
Ecotoxicity and Toxicity:

Biodegradability:

Non biodegradable:

Bioaccumulation or Bioaccumulation:

Other harmful effects:
No information available.
Part 13: Disposal of Waste
Waste nature:

Disposal method:
Dispose of by incineration method. The nitrogen oxides discharged from the incinerator are removed by a scrubber.
Disposal precautions:

Part 14: Transportation Information
Dangerous Goods Number:
32159
UN Number:
1648
Packaging label:

Packaging category:
O52
Packaging method:
Small opening steel drum; Ordinary wooden box outside the ampoule bottle; Screw mouth glass bottles, iron cap pressed mouth glass bottles, plastic bottles, or ordinary wooden boxes outside metal drums (cans).
Transportation precautions:
Transport vehicles should be equipped with corresponding types and quantities of fire-fighting equipment and emergency response equipment for leaks during transportation. It is best to transport in the morning and evening during summer. The tank truck used for transportation should have a grounding chain, and a perforated partition can be installed inside the tank to reduce static electricity generated by vibration. It is strictly prohibited to mix and transport with oxidants, reducing agents, acids, bases, flammable or combustible materials, edible chemicals, etc. During transportation, it should be protected from direct sunlight, rain, and high temperatures. When stopping midway, one should stay away from sources of fire, heat, and high temperature areas. The exhaust pipe of the vehicle carrying the item must be equipped with a flame retardant device, and the use of mechanical equipment and tools that are prone to generating sparks for loading and unloading is prohibited. When transporting by road, follow the prescribed route and do not stay in residential or densely populated areas. It is prohibited to slip during railway transportation. It is strictly prohibited to use wooden boats or cement boats for bulk transportation.
Part 15: Regulatory Information
Regulatory Information
The Regulations on the Safety Management of Hazardous Chemicals (issued by the State Council on February 17, 1987), the Implementation Rules for the Regulations on the Safety Management of Hazardous Chemicals (Hua Lao Fa [1992] No. 677), the Regulations on the Safe Use of Chemicals in the Workplace ([1996] Labor Department Fa No. 423) and other regulations have made corresponding provisions for the safe use, production, storage, transportation, loading and unloading of hazardous chemicals; The classification and labeling of commonly used hazardous chemicals (GB 13690-92) classify this substance as a Class 3.2 flammable liquid with a flash point.
Part 16: Other Information
References:

Filling time:

Filling department:

Data auditing unit:

Modification instructions:

Other information:

MSDS modification date:


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